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EDITED BY:Marc S. Ernstoff, MD – Roswell Park Comprehensive Cancer CenterIgor Puzanov, MD, MSCI, FACP – Roswell Park Comprehensive Cancer CenterCaroline Robert, MD, PhD – Institut Gustave RoussyAdi Diab, MD – The University of Texas MD Anderson Cancer CenterPeter Hersey, MD, PhD – University of Sydney
The Society for Immunotherapy of Cancer’s handbook, SITC's Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with U.S. Food and Drug Administration (FDA)-approved cancer immunotherapy treatments. Written by world-recognized thought leaders in the field of cancer immunotherapy, this text provides thorough coverage of the toxicity and management of adverse events experienced during treatment with immune checkpoint inhibitors.Separated into two parts, Part I of the textbook contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is organized by the impact of toxicities on major organ sites throughout the body. It begins with general principles of immune-related toxicity management followed by chapters which focus on specific toxicities: rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, ocular toxicities and others. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects. Part II concludes with a discussion on the management of special patient populations, such as patients with autoimmune disease and geriatric patients, as well as chapters on fatigue management and cost effectiveness.This textbook is an essential resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the academic and community hospital settings.This handbook will also provide to clinicians:
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Publication Date: March 28, 2019Page Count: 240Product Form: Paperback/soft coverISBN: 9780826172143
“Given the important and exciting advances in cancer immunotherapy, it is not surprising that there is no dearth of books on the subject. Despite the competition, however, this book is a unique masterpiece and a must-have comprehensive resource for anyone interested in this area and for every medical library.”Score: 100, 5 Stars, Doody’s Medical Reviews
When purchasing Cancer Immunotherapy Principles and Practice, 2nd Ed. via Springer Publishing, receive a 20% discount, plus free shipping with discount code: SITC20 (Cannot be combined with any other offers).
EDITED BY:Lisa H. Butterfield, PhD - Past SITC PresidentHoward L. Kaufman, MD, FACS - Past SITC PresidentFrancesco M. Marincola, MD - Past SITC President
Thoroughly updated to reflect major advances in the field of immuno-oncology in recent years, Cancer Immunotherapy Principles and Practice, 2nd Ed., from the Society for Immunotherapy of Cancer (SITC), remains the definitive resource for information on tumor immunology and cancer immunotherapy treatments. An essential reference for both novice and experienced cancer researchers, oncologists, and related practitioners alike, the book not only guides readers through the fundamental scientific principles of the field all the way to translational and practical clinical applications for treating and managing oncologic disease, but also provides a comprehensive understanding of the regulatory processes that support the safe and effective delivery of immunotherapy to patients with cancer.
The expanded and updated second edition now spans 68 chapters, including 12 new chapters, covering major topics and innovations that have shaped the rapid development of immunotherapy and its ascension into the standard of care as first-line treatment for a growing number of disease settings. New to this edition are chapters with deeper insight into our understanding of cancer genomics and determinants of response, immunogenic cell death, cancer and stromal cell-intrinsic pathways of immune resistance, cancer immune exclusion, adoptive cell therapy, metabolomics, tumor mutation burden, immunotherapy in combination with radiation therapy, synthetic biology, and more. Complete with detailed illustrations, tables, and key points for targeted reference, Cancer Immunotherapy Principles and Practice, 2nd Ed. is the most comprehensive and authoritative resource for scientists and clinicians looking to expand their knowledge base of this dynamic field.
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Publication Date: September 1, 2021Page Count: 941Product Form: HardbackISBN: 9780826137425eBook ISBN: 9780826137432